In just a few hours at 08:15 UT / 03:15 ET NASA TV will carry coverage of the docking of the S.S. Gene Cernan cargo-spaceship to the International Space Station.
An hour later coverage begins on the attempted launch of an American weather satellite. The satellite will be put into a polar orbit and as you can imagine is packed with the latest technology — have a look at the JPSS-1 mission here.
If all goes well coverage can be found here at 08:20 UT / 03:20 ET.
I know, for the North/South American east and points there to the west it might not be the most opportune time so with any luck replays will be available.